KN-92 Phosphate

This product is for research use only, not for human use. We do not sell to patients.

KN-92 Phosphate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1350Check With Us
500mg$1980Check With Us
1g$2970Check With Us

Cat #: V2802 CAS #: 1135280-28-2 Purity ≥ 98%

Description: KN-92 Phosphate, the phosphate salt of KN-92, is an inactive derivative of KN-93.

References: An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448.

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Molecular Weight (MW)554.98
Molecular FormulaC24H28ClN2O7PS
CAS No.1135280-28-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 25mg/mLrr
Water: N/Arr
Ethanol: N/A
SMILES CodeCN(C/C=C/C1=CC=C(Cl)C=C1)CC2=CC=CC=C2NS(=O)(C3=CC=C(OC)C=C3)=O.O=P(O)(O)O
SynonymsKN-92 phosphate; KN-92; KN 92; KN92.
ProtocolIn VitroKN-93 (5-50 μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8019 mL9.0093 mL18.0187 mL36.0373 mL
5mM0.3604 mL1.8019 mL3.6037 mL7.2075 mL
10mM0.1802 mL0.9009 mL1.8019 mL3.6037 mL
20mM0.0901 mL0.4505 mL0.9009 mL1.8019 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.