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Naltrexone HCl

This product is for research use only, not for human use. We do not sell to patients.

Naltrexone HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$150Check With Us
2g$250Check With Us
5g$400Check With Us
email: [email protected]        [email protected]

Cat #: V3777 CAS #: 16676-29-2 Purity ≥ 98%

Description: Naltrexone HCl is a potent opioid receptor antagonist used mainly in the management of alcohol dependence and opioid dependence.

References: Psychopharmacology (Berl). 1998 Sep;139(1-2):53-61; Eur J Pharmacol. 1999 Jun 25;374(3):321-7.  

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Molecular Weight (MW)377.86
Molecular FormulaC20H23NO4.HCl
CAS No.16676-29-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 14 mg/mL (37.1mM)rr
Water: 14 mg/mL (37.1mM)rr
Ethanol:<1 mg/mL
SMILES CodeC1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O
SynonymsNaltrexone, EN-1639A, EN 1639A, EN1639A; Revia, Depade, Vivitrol, Celupan
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6465 mL13.2324 mL26.4648 mL52.9297 mL
5mM0.5293 mL2.6465 mL5.2930 mL10.5859 mL
10mM0.2646 mL1.3232 mL2.6465 mL5.2930 mL
20mM0.1323 mL0.6616 mL1.3232 mL2.6465 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.