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Cytisine (Baphitoxine, Cytisinicline, Sophorine)

This product is for research use only, not for human use. We do not sell to patients.

Cytisine (Baphitoxine, Cytisinicline, Sophorine)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$650Check With Us
5g$1150Check With Us
10g$1725Check With Us

Cat #: V1169 CAS #: 485-35-8 Purity ≥ 98%

Description: Cytisine (Baphitoxine,Sophorine; Citizin; HSDB-3560; Laburnin; NSC-407282; Cytisinicline), a nicotinic acetylcholine receptor agonist, is a naturally occuring alkaloid found in several plant genera, such as Laburnum and Cytisus of the family Fabaceae.

References: Grebenstein PE, et al. The effects of noncontingent and self-administered cytisine on body weight and meal patterns in male Sprague-Dawley rats. Pharmacol Biochem Behav. 2013 Sep;110:192-200.

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Promise
Molecular Weight (MW)190.24
Molecular FormulaC11H14N2O
CAS No.485-35-8
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 38 mg/mL (199.7 mM)rr
Water: 38 mg/mL (199.7 mM)rr
Ethanol: 38 mg/mL (199.7 mM)
SMILES CodeO=C1C=CC=C2N1C[C@]3([H])CNC[C@@]2([H])C3
SynonymsBaphitoxine,Sophorine; Citizin; HSDB 3560; Laburnin; NSC 407282; NSC407282; HSDB3560; HSDB-3560; NSC-407282; Sophorin; Cytisine; Cytisinicline
ProtocolIn VivoTotal pellet intake increases during Cytisinicline (Cytisine) substitution relative to nicotine and animals self-administered Cytisine significantly less than nicotine
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.2565 mL26.2826 mL52.5652 mL105.1304 mL
5mM1.0513 mL5.2565 mL10.5130 mL21.0261 mL
10mM0.5257 mL2.6283 mL5.2565 mL10.5130 mL
20mM0.2628 mL1.3141 mL2.6283 mL5.2565 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.