Bethanechol chloride

This product is for research use only, not for human use. We do not sell to patients.

Bethanechol chloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$280Check With Us
50g$450Check With Us
100g$675Check With Us

Cat #: V1179 CAS #: 590-63-6 Purity ≥ 98%

Description: Bethanechol Chloride (also known as Carbamyl-β-methylcholine chloride) is a parasympathomimetic choline carbamate and an analog of acetylcholine with a long duration of action due to improved metabolic stability.

References: Julia Yuen Hang Liu, et al. Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity: role of muscarinic versus nicotinic receptors. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319(1):G97-G107.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)196.68
Molecular FormulaC7H17N2O2.Cl
CAS No.590-63-6
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 39 mg/mL (198.3 mM)rr
Water: 39 mg/mL (198.3 mM)rr
Ethanol: 39 mg/mL (198.3 mM)
SMILES CodeCC(OC(N)=O)C[N+](C)(C)C.[Cl-]
SynonymsCarbamyl-β-methylcholine chloride
ProtocolIn VivoBethanechol (2-12 mg/kg; i.p.) induces drinking and increases urine output of rats in a dose-dependent fashion
Animal modelFemale rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g)
Dosages2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
AdministrationIntraperitoneal injection
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.0844 mL25.4220 mL50.8440 mL101.6880 mL
5mM1.0169 mL5.0844 mL10.1688 mL20.3376 mL
10mM0.5084 mL2.5422 mL5.0844 mL10.1688 mL
20mM0.2542 mL1.2711 mL2.5422 mL5.0844 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.