Acetylcholine Chloride

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25g	$250	Check With Us
50g	$350	Check With Us
100g	$525	Check With Us

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Cat #: V1177 CAS #: 60-31-1 Purity ≥ 98%

Description: Acetylcholine Chloride (ACh chloride; Ovisot; TL-1505; TL-1505) is an organic chemical and a common neurotransmitter found in the central and peripheral nerve system that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical released by nerve cells to send signals to other cells.

References: P F Zabrodskii, et al. Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production. Bull Exp Biol Med. 2011 Jan;150(3):340-2.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	181.66
Molecular Formula	C7H16NO2.Cl
CAS No.	60-31-1
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: > 10 mMrr
	Water: > 10 mMrr
	Ethanol: > 10 mM
Solubility In Vivo	Chemical Name: (2-Acetoxyethyl)trimethylammonium chloride InChi Key: JUGOREOARAHOCO-UHFFFAOYSA-M InChi Code: InChI=1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1 SMILES Code: C[N+](C)(CCOC(C)=O)C.[Cl-]
SMILES Code	C[N+](C)(CCOC(C)=O)C.[Cl-]
Synonyms	TL 1505; ACh chloride; Ovisot; TL-1505; TL-1505; Acetylcholine chloride.

Protocol	In Vivo	Acetylcholine chloride (ACh chloride; SC; 20 mg/kg; single dose) induces pronounced cholinergic stimulation and increase of mouse survival in experimental infection
	Animal model	Male and female out-bred albino mice weighing 18-22 g (sepsis)
	Dosages	20 mg/kg

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	5.5048 mL	27.5239 mL	55.0479 mL	110.0958 mL
5mM	1.1010 mL	5.5048 mL	11.0096 mL	22.0192 mL
10mM	0.5505 mL	2.7524 mL	5.5048 mL	11.0096 mL
20mM	0.2752 mL	1.3762 mL	2.7524 mL	5.5048 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.