Nitenpyram

This product is for research use only, not for human use. We do not sell to patients.

Nitenpyram
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$400Check With Us
5g$700Check With Us
10g$1050Check With Us

Cat #: V1166 CAS #: 150824-47-8 Purity ≥ 98%

Description: Nitenpyram (trade names Capstar, Bestguard), an insect neurotoxin of the neonicotinoid class, is a fast and long-acting, and orally bioavailable nicotinic acetylcholine receptor (AchR) agonist with neural signaling-blocking activity.

References: Vo DT, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33(4):315-22.

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Product Promise

Promise
Molecular Weight (MW)270.72
Molecular FormulaC11H15ClN4O2
CAS No.150824-47-8
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 54 mg/mL (199.5 mM)rr
Water: N/Arr
Ethanol: 54 mg/mL (199.5 mM)
SMILES CodeO=[N+](/C=C(NC)/N(CC1=CC=C(Cl)N=C1)CC)[O-]
SynonymsNitenpyram; Capstar, Bestguard
ProtocolIn VivoNitenpyram is administered orally (1 mg/kg) for the short-term control of fleas in dogs and cats. Fleas start to fall from the animals 30 minutes post-administration and one dose can protect animals for 1-2 days
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.6939 mL18.4693 mL36.9385 mL73.8771 mL
5mM0.7388 mL3.6939 mL7.3877 mL14.7754 mL
10mM0.3694 mL1.8469 mL3.6939 mL7.3877 mL
20mM0.1847 mL0.9235 mL1.8469 mL3.6939 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.