CNQX
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $550 | Check With Us |
| 500mg | $800 | Check With Us |
| 1g | $1200 | Check With Us |
: Cat #: V33762 CAS #: 115066-14-3 Purity ≥ 99%
Description: CNQX (FG9065; FG-9065; 6-cyano-7-nitroquinoxaline-2,3-dione) is an AMPA/kainate antagonist that inhibits AMPA and kainate receptors with IC50 values of 0.3 μM, 1.5 μM, respectively.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 232.15 |
|---|---|
| Molecular Formula | C₉H₄N₄O₄ |
| CAS No. | 115066-14-3 |
| Synonyms | FG9065 |
| Protocol | In Vitro | CNQX (FG9065; 2-5 μM) reversibly blocks the Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP), while sparing the fast and slow GABA-mediated inhibition in superfusion of hippocampal slices |
|---|---|---|
| In Vivo | CNQX (FG9065; 2-5 μM) reversibly blocks the Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP), while sparing the fast and slow GABA-mediated inhibition in superfusion of hippocampal slices | |
| Animal model | Male Wistar rats weighing 180-200 g | |
| Dosages | Male Wistar rats weighing 180-200 g | |
| Administration | IP; 20 min before testing |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.3076 mL | 21.5378 mL | 43.0756 mL | 86.1512 mL |
| 5mM | 0.8615 mL | 4.3076 mL | 8.6151 mL | 17.2302 mL |
| 10mM | 0.4308 mL | 2.1538 mL | 4.3076 mL | 8.6151 mL |
| 20mM | 0.2154 mL | 1.0769 mL | 2.1538 mL | 4.3076 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.