Zaltoprofen (CN100)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $350 | Check With Us |
| 10g | $550 | Check With Us |
| 20g | $825 | Check With Us |
: Cat #: V1069 CAS #: 74711-43-6 Purity ≥ 98%
Description: Zaltoprofen (CN 100; CN-100; CN100), a nonsteroidal anti-inflammatory drug (NSAID), is a potent inhibitor of COX-1 and COX-2 enzymes with potential anti-inflammatory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 298.36 |
|---|---|
| Molecular Formula | C17H14O3S |
| CAS No. | 74711-43-6 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 60 mg/mL (201.1 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 31 mg/mL (103.9 mM) | |
| SMILES Code | O=C(O)C(C)C1=CC=C(C(C2)=C1)SC3=CC=CC=C3C2=O |
| Synonyms | CN 100; CN-100; CN100 |
| Protocol | In Vitro | Zaltoprofen (0.1-1 μM; 5 min) inhibits the bradykinin-induced increase of [Ca2+]i in DRG cells |
|---|---|---|
| In Vivo | Zaltoprofen (3-30 mg/kg; a single p.o.) inhibits the acetic acid-induced writhing response of mice in a dose-dependent manner | |
| Animal model | Eight-week-old male Wistar rats were injected Bradykinin every 15 min | |
| Dosages | 5, 10, 20 mg/kg |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3517 mL | 16.7583 mL | 33.5166 mL | 67.0331 mL |
| 5mM | 0.6703 mL | 3.3517 mL | 6.7033 mL | 13.4066 mL |
| 10mM | 0.3352 mL | 1.6758 mL | 3.3517 mL | 6.7033 mL |
| 20mM | 0.1676 mL | 0.8379 mL | 1.6758 mL | 3.3517 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.