YH239-EE
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1250 | Check With Us |
| 1g | $1950 | Check With Us |
| 5g | $4935 | Check With Us |
: Cat #: V0044 CAS #: 1364488-67-4 Purity ≥ 98%
Description: YH239-EE (YH239-EE; YH239EE; YH239 EE), the ethyl ester of YH239, is a novel and highly potent antagonist of p53/MDM2 (murine double minute 2) protein protein interaction.
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| Molecular Weight (MW) | 504.41 |
|---|---|
| Molecular Formula | C25H27Cl2N3O4 |
| CAS No. | 1364488-67-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (198.3 mM)r |
| Water:<1 mg/mL (slightly soluble or insoluble)r | |
| Ethanol: 18 mg/mL (35.7 mM) | |
| SMILES Code | O=C(C(N1)=C(C(N(CC2=CC=C(Cl)C=C2)C=O)C(NC(C)(C)C)=O)C3=C1C=C(Cl)C=C3)OCC |
| Synonyms | YH239 Ethylester; YH239-EE; YH239EE; YH239 EE; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9825 mL | 9.9126 mL | 19.8251 mL | 39.6503 mL |
| 5mM | 0.3965 mL | 1.9825 mL | 3.9650 mL | 7.9301 mL |
| 10mM | 0.1983 mL | 0.9913 mL | 1.9825 mL | 3.9650 mL |
| 20mM | 0.0991 mL | 0.4956 mL | 0.9913 mL | 1.9825 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.