10-Deacetyl-7-xylosyl paclitaxel

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$450	Check With Us
250mg	$850	Check With Us
500mg	$1275	Check With Us

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Cat #: V28844 CAS #: 90332-63-1 Purity ≥ 99%

Description: 10-Deacetyl-7-xylosyl paclitaxel, a Paclitaxel analog, is a metabolite of Paclitaxel (TAXOL) which is a microtubule stabilizing agent/tubulin inhibitor and chemotherapeutic drug approved to treat various cancers.

References: Jiang S, et al. Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int J Oncol. 2008 Jul;33(1):103-11.

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Molecular Weight (MW)	943.98
Molecular Formula	C50H57NO17
CAS No.	90332-63-1
SMILES Code	C[C@@]1([C@@]([H])([C@@](CO2)(OC(C)=O)[C@]2(C[C@@H]1O[C@@]([H])([C@H](O)[C@H]3O)OC[C@H]3O)[H])[C@@H]4OC(C5=CC=CC=C5)=O)C([C@H](O)C6=C([C@H](C[C@@]4(C6(C)C)O)OC([C@@H]([C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)O)=O)C)=O
Synonyms	10-deacetyl-7-xylosyl Paclitaxel

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.0593 mL	5.2967 mL	10.5934 mL	21.1869 mL
5mM	0.2119 mL	1.0593 mL	2.1187 mL	4.2374 mL
10mM	0.1059 mL	0.5297 mL	1.0593 mL	2.1187 mL
20mM	0.0530 mL	0.2648 mL	0.5297 mL	1.0593 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.