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AZD-5991 RACEMATE

This product is for research use only, not for human use. We do not sell to patients.

AZD-5991 RACEMATE
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1910Check With Us
200mg$2865Check With Us
500mg$4830Check With Us

Cat #: V4342 CAS #: 2143010-83-5 Purity ≥ 98%

Description: AZD-5991 racemate, the racemate of AZD5991, is a Mcl-1 inhibitor (IC50<3 nM in FRET assay) with antitumor activity.

References: Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.

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Product Promise

Promise
Molecular Weight (MW)672.26
Molecular FormulaC35H34ClN5O3S2
CAS No.2143010-83-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SynonymsAZD-5991 Racemate
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4875 mL7.4376 mL14.8752 mL29.7504 mL
5mM0.2975 mL1.4875 mL2.9750 mL5.9501 mL
10mM0.1488 mL0.7438 mL1.4875 mL2.9750 mL
20mM0.0744 mL0.3719 mL0.7438 mL1.4875 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.