Leuprorelin | CAS 53714-56-0

Leuprorelin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
50mg	$165	To Be Confirmed
100mg	$250	To Be Confirmed
250mg	$450	To Be Confirmed
500mg	$750	To Be Confirmed

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Cat #: V18098 CAS #: 53714-56-0 Purity ≥ 99%

Description: Leuprorelin (A43818; NSC377526; A-43818; NSC-377526; leuprolide acetate; Leuprorelinum; Eligard) is a gonadotrophin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors. It has been used to treat a wide range of sex hormone-related disorders such as advanced prostatic cancer, endometriosis and precocious puberty. It acts primarily on the anterior pituitary, inducing a transient early rise in gonadotrophin release. With continued use, leuprorelin causes pituitary desensitisation and/or down-regulation, leading to suppressed circulating levels of gonadotrophins and sex hormones.

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Molecular Weight (MW)	1209.42
Molecular Formula	C59H84N16O12
CAS No.	53714-56-0
Synonyms	NSC-377526; NSC 377526; Leuprorelin; A-43818; A 43818; A43818; NSC377526; leuprolide acetate; Leuprorelinum; Eligard

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.8268 mL	4.1342 mL	8.2684 mL	16.5369 mL
5mM	0.1654 mL	0.8268 mL	1.6537 mL	3.3074 mL
10mM	0.0827 mL	0.4134 mL	0.8268 mL	1.6537 mL
20mM	0.0413 mL	0.2067 mL	0.4134 mL	0.8268 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.