Acrizanib (LHA-510)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2mg	$250	To Be Confirmed
5mg	$450	To Be Confirmed
10mg	$750	To Be Confirmed
25mg	$1250	To Be Confirmed
50mg	$1950	To Be Confirmed
100mg	$3250	To Be Confirmed

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Cat #: V10251 CAS #: 1229453-99-9 Purity ≥ 98%

Description: Acrizanib, formerly known as LHA510, is a novel, potent and selective angiogenesis inhibitor and VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration.

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Quality Control Documentation

Molecular Weight (MW)	445.4062
Molecular Formula	C20H18F3N7O2
CAS No.	1229453-99-9
Synonyms	Acrizanib; LHA510; LHA 510; LHA-510.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2451 mL	11.2257 mL	22.4514 mL	44.9028 mL
5mM	0.4490 mL	2.2451 mL	4.4903 mL	8.9806 mL
10mM	0.2245 mL	1.1226 mL	2.2451 mL	4.4903 mL
20mM	0.1123 mL	0.5613 mL	1.1226 mL	2.2451 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.