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| Size | Price | Stock |
|---|---|---|
| 5mg | $88 | 3-6 Days |
| 10mg | $130 | 3-6 Days |
| 25mg | $230 | 3-6 Days |
| 50mg | $400 | 3-6 Days |
| 100mg | $700 | 3-6 Days |
| 250mg | $1150 | 3-6 Days |
| 500mg | $1850 | 3-6 Days |
: Cat #: V12465 CAS #: 922139-31-9 Purity ≥ 98%
Description: Recilisib sodium (formerly known as ON 01210.Na; ON-01210; ON01210; EX-RAD), the soiumd salt of recilisib, is a radioprotectant that is being studies in phase 1 clinical trials by Onconova Therapeutics for the treatment of acute radiation syndrome. It is able to mitigate radiation damage through activation of the AKT pathway. Recilisib modifies cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation protection studies. It appears that Recilisib radioprotective mechanisms involve prevention of p53-dependent and independent radiation-induced apoptosis.
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| Molecular Weight (MW) | 358.7678 |
|---|---|
| Molecular Formula | C16H12ClNaO4S |
| CAS No. | 922139-31-9 |
| Synonyms | Recilisib sodium; ON 01210.Na; Ex-RAD; ON-01210; ON01210; ON01210 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7873 mL | 13.9366 mL | 27.8732 mL | 55.7464 mL |
| 5mM | 0.5575 mL | 2.7873 mL | 5.5746 mL | 11.1493 mL |
| 10mM | 0.2787 mL | 1.3937 mL | 2.7873 mL | 5.5746 mL |
| 20mM | 0.1394 mL | 0.6968 mL | 1.3937 mL | 2.7873 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.