SCH-79797 | CAS 245520-69-8

SCH-79797

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10mg	$200	To Be Confirmed
25mg	$420	To Be Confirmed
50mg	$650	To Be Confirmed
100mg	$1100	To Be Confirmed
250mg	$2000	To Be Confirmed

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Cat #: V14527 CAS #: 245520-69-8 Purity ≥ 98%

Description: SCH-79797 (SCH79797) is a novel, potent and selective PAR1 (protease activated receptor 1) antagonist with an IC50 of 70 nM and a Ki of 35 nM. SCH-79797 limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH 79797 protects against ischemia/reperfusion-induced arrhythmias in the rat hearts. SCH 79797 and its N-methyl analogue (SCH 203099) inhibited binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP, Ala-Phe(p-F)-Arg-ChA-HArg-[(3)H]Tyr-NH(2)) to PAR-1 with IC(50) values of 70 and 45 nM, respectively.

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Molecular Weight (MW)	371.488
Molecular Formula	C23H25N5
CAS No.	245520-69-8
Synonyms	SCH-79797; SCH 79797; SCH79797

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.6919 mL	13.4594 mL	26.9188 mL	53.8375 mL
5mM	0.5384 mL	2.6919 mL	5.3838 mL	10.7675 mL
10mM	0.2692 mL	1.3459 mL	2.6919 mL	5.3838 mL
20mM	0.1346 mL	0.6730 mL	1.3459 mL	2.6919 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.