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Cefpodoxime Proxetil

This product is for research use only, not for human use. We do not sell to patients.

Cefpodoxime Proxetil
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$2003-6 Days
500mg$3503-6 Days
1g$5003-6 Days
2g$7503-6 Days
5g$13503-6 Days

Cat #: V17851 CAS #: 87239-81-4 Purity ≥ 99%

Description: Cefpodoxime Proxetil (Doxef; CS-807; U-76252;) is a broad spectrum antibacterial agent that acts by binding to penicillin binding proteins (PBPs), thus inhibiting peptidoglycan synthesis, leading to disruption of bacterial cell wall biosynthesis. It is an ester prodrug of the active free acid metabolite Cefpodoxime, and is active against most Gram-positive and Gram-negative organisms. Cefpodoxime Proxetil has been widely used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea.

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Molecular Weight (MW)557.6
Molecular FormulaC21H27N5O9S2
CAS No.87239-81-4
SMILES Code CC(C)OC(=O)OC(C)OC(=O)C1=C(CS[C@H]2N1C(=O)[C@H]2NC(=O)/C(=N/OC)/C3=CSC(=N3)N)COC
SynonymsBanan; Vantin; Cefpodoxime Proxetil; CS-807; Doxef; U 76252; Doxef; CS 807; Toraxim; cephalosporin 807; CS 807; U-76,252
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7934 mL8.9670 mL17.9340 mL35.8680 mL
5mM0.3587 mL1.7934 mL3.5868 mL7.1736 mL
10mM0.1793 mL0.8967 mL1.7934 mL3.5868 mL
20mM0.0897 mL0.4484 mL0.8967 mL1.7934 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.