NIH-12848

This product is for research use only, not for human use. We do not sell to patients.

NIH-12848
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$883-6 Days
10mg$1303-6 Days
25mg$2303-6 Days
50mg$4003-6 Days
100mg$7003-6 Days
250mg$12503-6 Days
500mg$19503-6 Days

Cat #: V26502 CAS #: 959551-10-1 Purity ≥ 99%

Description: NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.

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Molecular Weight (MW)385.4082
Molecular FormulaC20H14F3N3S
CAS No.959551-10-1
SynonymsNIH-12848; NIH 12848; NIH12848, NCGC00012848-02.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5947 mL12.9733 mL25.9465 mL51.8930 mL
5mM0.5189 mL2.5947 mL5.1893 mL10.3786 mL
10mM0.2595 mL1.2973 mL2.5947 mL5.1893 mL
20mM0.1297 mL0.6487 mL1.2973 mL2.5947 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.