Carboxyamidotriazole orotate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5mg	$150	To Be Confirmed
10mg	$250	To Be Confirmed
25mg	$450	To Be Confirmed
50mg	$700	To Be Confirmed

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Cat #: V17563 CAS #: 187739-60-2 Purity ≥ 99%

Description: Carboxyamidotriazole orotate is the orotate salt form of carboxyamidotriazole (CAI; RFE-007; L-651582; NSC-609974), which is a novel and potent inhibitor of both cAMP-phosphodiesterases and GMP-phosphodiesterases with anti-tumor, antiangiogenic and anti-inflammatory activity. Also an inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways.

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Molecular Weight (MW)	719.68
Molecular Formula	C23H16Cl3IN7O6
CAS No.	187739-60-2

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.3895 mL	6.9475 mL	13.8951 mL	27.7901 mL
5mM	0.2779 mL	1.3895 mL	2.7790 mL	5.5580 mL
10mM	0.1390 mL	0.6948 mL	1.3895 mL	2.7790 mL
20mM	0.0695 mL	0.3474 mL	0.6948 mL	1.3895 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.