Ganaxolone

This product is for research use only, not for human use. We do not sell to patients.

Ganaxolone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$1503-6 Days
10mg$2503-6 Days
25mg$4503-6 Days
50mg$7503-6 Days
100mg$12503-6 Days
250mg$19503-6 Days

Cat #: V17221 CAS #: 38398-32-2 Purity ≥ 99%

Description: Ganaxolone (CCD-1042; C-1042; Ztalmy) is a novel, CNS-active and potent GABAA modulator. As of March 2022, the US FDA has approved Ztalmy (ganaxolone) to treat seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) in patients 2 years of age and older. This is the first treatment for seizures associated with CDD and the first treatment specifically for CDD. Ganaxolone acts on well-characterized targets in the brain known to have anxiolytic and anticonvulsant effects.

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Molecular Weight (MW)332.528
Molecular FormulaC22H36O2
CAS No.38398-32-2
SMILES Code CC([C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@](C)(O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
SynonymsCCD-1042; CCD 1042; C1042; CCD-1042; Ztalmy
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0073 mL15.0363 mL30.0727 mL60.1453 mL
5mM0.6015 mL3.0073 mL6.0145 mL12.0291 mL
10mM0.3007 mL1.5036 mL3.0073 mL6.0145 mL
20mM0.1504 mL0.7518 mL1.5036 mL3.0073 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.