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Olodanrigan sodium (PD126055; EMA 401)

This product is for research use only, not for human use. We do not sell to patients.

Olodanrigan sodium (PD126055; EMA 401)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$250To Be Confirmed
10mg$450To Be Confirmed
25mg$800To Be Confirmed
50mg$1300To Be Confirmed
email: [email protected]        [email protected]

Cat #: V26877 CAS #: 1316755-17-5 Purity ≥ 99%

Description: Olodanrigan sodium (EMA401; PD126055; EMA-401), a novel, orally bioavailable, peripherally restricted and highly selective AT2R (angiotensin II type 2 receptor) antagonist, can be potentially used for treatment of postherpetic neuralgia (PHN). Inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. It is being developed as a neuropathic pain therapeutic agent.

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Molecular FormulaC32H28NNaO5
CAS No.1316755-17-5
SMILES CodeO=C([C@H]1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC4=C(C(OCC5=CC=CC=C5)=C(OC)C=C4)C1)[O-].[Na+] 
SynonymsEMA401; PD-126055; EMA-401; PD 126055; EMA 401; EMA401 sodium; PD126055
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.