Melevodopa hydrochloride

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$130	3-6 Days
5g	$200	3-6 Days
10g	$330	3-6 Days
25g	$600	3-6 Days

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Cat #: V25248 CAS #: 1421-65-4 Purity ≥ 99%

Description: Melevodopa HCl (ST-41769; ST 41769; trade name Levomet), the hydrochloride salt of Melevodopa which is the methyl ester and prodrug form of levodopa, is a dopaminergic agent used as an anti-Dyskinesia drug. It has also been used in combination with carbidopa for the treatment of PD/Parkinson's disease.

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Molecular Weight (MW)	247.68
Molecular Formula	C10H14ClNO4
CAS No.	1421-65-4
Synonyms	ST-41769; ST 41769

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.0375 mL	20.1873 mL	40.3747 mL	80.7494 mL
5mM	0.8075 mL	4.0375 mL	8.0749 mL	16.1499 mL
10mM	0.4037 mL	2.0187 mL	4.0375 mL	8.0749 mL
20mM	0.2019 mL	1.0094 mL	2.0187 mL	4.0375 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.