Ciliobrevin D

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10mg	$200	To Be Confirmed
25mg	$400	To Be Confirmed
50mg	$600	To Be Confirmed
100mg	$950	To Be Confirmed

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Cat #: V18331 CAS #: 1370554-01-0 Purity ≥ 99%

Description: Ciliobrevin D is a novel and potent AAA+ ATPase motor cytoplasmic dynein inhibitor, also inhibits Hedgehog (Hh) signaling and primary cilia formation and dynein-dependent microtubule gliding and ATPase activity in vitro.

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Molecular Weight (MW)	392.62
Molecular Formula	C17H8Cl3N3O2
CAS No.	1370554-01-0

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5470 mL	12.7350 mL	25.4699 mL	50.9398 mL
5mM	0.5094 mL	2.5470 mL	5.0940 mL	10.1880 mL
10mM	0.2547 mL	1.2735 mL	2.5470 mL	5.0940 mL
20mM	0.1273 mL	0.6367 mL	1.2735 mL	2.5470 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.