This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 25mg | $250 | 3-6 Days |
| 50mg | $450 | 3-6 Days |
| 100mg | $750 | 3-6 Days |
| 250mg | $1250 | 3-6 Days |
| 500mg | $1750 | 3-6 Days |
: Cat #: V22425 CAS #: 1160927-48-9 Purity ≥ 98%
Description: IDE1 (Inducer of definitive endoderm 1) is a novel, potent and cell-permeable inducer of definitive endoderm formation with EC50 of 125 nM). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression. It induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 125 nM, SOX17 expression was induced in mouse ES cells.
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| Molecular Formula | C15H18N2O5 |
|---|---|
| CAS No. | 1160927-48-9 |
| SMILES Code | O=C(O)CCCCCC(N/N=C/C1=CC=CC=C1C(O)=O)=O |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.