IACS-8779 disodium

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V50615 CAS #: 2243079-27-6 Purity ≥ 99%

Description: IACS-8779 disodium is a novel and highly potent stimulator of interferon genes (STING) agonist with antitumor efficacy.It activates the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma.

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Molecular Weight (MW)	733.52
Molecular Formula	C21H23N9Na2O10P2S2
CAS No.	2243079-27-6

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.3633 mL	6.8164 mL	13.6329 mL	27.2658 mL
5mM	0.2727 mL	1.3633 mL	2.7266 mL	5.4532 mL
10mM	0.1363 mL	0.6816 mL	1.3633 mL	2.7266 mL
20mM	0.0682 mL	0.3408 mL	0.6816 mL	1.3633 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.