LP-403812 | CAS 1142050-84-7

LP-403812

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V24430 CAS #: 1142050-84-7 Purity ≥ 99%

Description: LP-403812 is a novel and potent small molecule inhibitor of the PROT proline transporter with an IC(50) of approximately 0.1μM on both recombinant human and mouse PROT without significant inhibition of glycine and dopamine transporters at concentrations up to 10μM.

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Molecular Weight (MW)	494.66
Molecular Formula	C26H34N6O2S
CAS No.	1142050-84-7
Synonyms	LP-403812; LP 403812; LP403812.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0216 mL	10.1080 mL	20.2159 mL	40.4318 mL
5mM	0.4043 mL	2.0216 mL	4.0432 mL	8.0864 mL
10mM	0.2022 mL	1.0108 mL	2.0216 mL	4.0432 mL
20mM	0.1011 mL	0.5054 mL	1.0108 mL	2.0216 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.