MYLS22
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $200 | 3-6 Days |
| 100mg | $300 | 3-6 Days |
| 250mg | $450 | 3-6 Days |
| 500mg | $650 | 3-6 Days |
: Cat #: V41464 CAS #: 306959-01-3 Purity ≥ 99%
Description: MYLS22 (MYL-S22) is a novel and specific optic atrophy 1 (OPA1) inhibitor with anti-cancer and anti-angiogenesis activity.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 443.525 |
|---|---|
| Molecular Formula | C24H21N5O2S |
| CAS No. | 306959-01-3 |
| SMILES Code | O=C(C(S1)=CC2=C1N(C3=CC=CC=C3)N=C2C)NC4=C(C)N(C)N(C5=CC=CC=C5)C4=O |
| Synonyms | MYLS-22; MYLS22 |
| Protocol | In Vivo | MYLS22 (10 mg/kg/die; peritumoral injection; every 2 days for 14 days) causes the tumor growth curtailed mice[1]. Animal Model: 6-week-old C57BL6/J mice with B16F10 melanomas. Dosage: 10 mg/kg/die Administration: Peritumoral injection; every 2 days for 14 days Result: Caused the tumor growth curtailed. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2547 mL | 11.2733 mL | 22.5466 mL | 45.0933 mL |
| 5mM | 0.4509 mL | 2.2547 mL | 4.5093 mL | 9.0187 mL |
| 10mM | 0.2255 mL | 1.1273 mL | 2.2547 mL | 4.5093 mL |
| 20mM | 0.1127 mL | 0.5637 mL | 1.1273 mL | 2.2547 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.