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| Size | Price | Stock |
|---|---|---|
| 250mg | $200 | 3-6 Days |
| 500mg | $300 | 3-6 Days |
| 1g | $500 | 3-6 Days |
| 2g | $850 | 3-6 Days |
: Cat #: V38852 CAS #: 1553-56-6 Purity ≥ 99%
Description: 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid; 3-oxoLCA; 3-Oxo-5β-cholan-24-oic Acid; 3-Oxo- 5β-cholanic Acid; 3-Ketolithocholic Acid), a bile acid metabolite, is a major metabolite of lithocholic acid (LCA) formed from LCA by the cytochrome P450 (CYP) isoform CYP3A4. It is an agonist of G protein-coupled bile acid activated receptor 1 (GP-BAR1/TGR5; EC50 = 0.27 μM), vitamin D receptor (VDR; EC50 = 3 μM), and farnesoid X receptor (FXR) in cell-based reporter assays. It also binds to the human pregnane X receptor (PXR; IC50 = 15 μM) and activates mouse and human PXRs in cell-based reporter assays when used at a concentration of 100 μM.
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| Molecular Weight (MW) | 374.56 |
|---|---|
| Molecular Formula | C₂₄H₃₈O₃ |
| CAS No. | 1553-56-6 |
| Synonyms | Dehydrolithocholic acid; 3-oxoLCA; <span class="pull-left col-xs-9 col-sm-8">3-Oxo-5β-cholan-24-oic Acid; 3-Oxo- 5β-cholanic Acid |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6698 mL | 13.3490 mL | 26.6980 mL | 53.3960 mL |
| 5mM | 0.5340 mL | 2.6698 mL | 5.3396 mL | 10.6792 mL |
| 10mM | 0.2670 mL | 1.3349 mL | 2.6698 mL | 5.3396 mL |
| 20mM | 0.1335 mL | 0.6674 mL | 1.3349 mL | 2.6698 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.