6-Amino-5-azacytidine

This product is for research use only, not for human use. We do not sell to patients.

6-Amino-5-azacytidine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1350To Be Confirmed
200mg$2025To Be Confirmed
500mg$3420To Be Confirmed

Cat #: V34039 CAS #: 105331-00-8 Purity ≥ 99%

Description: 6-Amino-5-azacytidine, an aminated derivative of Azacytidine, is able to inhibit the growth of bacteria E. coli.

References: Alois Pískala, et al. Synthesis, molecular conformation and biological activity of 6-amino-5-azacytidine. Collect. Czech. Chem. Commun. 1989, 54, 2502-2512.

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Molecular Weight (MW)259.22
Molecular FormulaC8H13N5O5
CAS No.105331-00-8
SMILES CodeO=C1N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C(N)=NC(N)=N1
Synonyms6-Amino-5-azacytidine
ProtocolIn Vitro6-Amino-5-azacytidine has an ID50 of 33.9 μM against CCRF-CEM cells and inhibits the growth of WI-L2 cells by 39% at 100 μM.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.8577 mL19.2886 mL38.5773 mL77.1545 mL
5mM0.7715 mL3.8577 mL7.7155 mL15.4309 mL
10mM0.3858 mL1.9289 mL3.8577 mL7.7155 mL
20mM0.1929 mL0.9644 mL1.9289 mL3.8577 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.