(5Z,2E)-CU-3 | CAS 1815598-71-0

(5Z,2E)-CU-3

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1150	To Be Confirmed
200mg	$1725	To Be Confirmed
500mg	$2910	To Be Confirmed

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Cat #: V32186 CAS #: 1815598-71-0 Purity ≥ 99%

Description: (5Z,2E)-CU-3 is a novel, potent and selective diacylglycerol kinase alpha (DGKalpha) inhibitor with an IC50 value of 0.6 μM, attenuating cancer cell proliferation and simultaneously enhancing immune responses including anti-cancer immunity.

References: Liu K, et al. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response. J Lipid Res. 2016 Mar;57(3):368-79.

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Molecular Weight (MW)	392.47
Molecular Formula	C16H12N2O4S3
CAS No.	1815598-71-0
Synonyms	(5Z,2E)-CU-3

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5480 mL	12.7398 mL	25.4797 mL	50.9593 mL
5mM	0.5096 mL	2.5480 mL	5.0959 mL	10.1919 mL
10mM	0.2548 mL	1.2740 mL	2.5480 mL	5.0959 mL
20mM	0.1274 mL	0.6370 mL	1.2740 mL	2.5480 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.