4-Hydroxynonenal

This product is for research use only, not for human use. We do not sell to patients.

4-Hydroxynonenal
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1080Check With Us
250mg$1725Check With Us
500mg$2585Check With Us

Cat #: V40672 CAS #: 75899-68-2 Purity ≥ 98%

Description: 4-Hydroxynonenal, an α,β unsaturated hydroxyalkenal, is a novel and potent inhibitor of acetaldehyde dehydrogenase 2 (ALDH2) widely used as a marker of lipid peroxidation/oxidative/nitrosative stress biomarke.

References: Zhong H, et al. Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: focusing on mitochondria. Redox Biol. 2015;4:193-9.

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Product Promise

Promise
Molecular Weight (MW)156.22
Molecular FormulaC9H16O2
CAS No.75899-68-2
SMILES Code CCCCCC(O)/C=C/C=O
Synonyms4-hydroxy Nonenal; 4-hydroxynonenal
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.4012 mL32.0061 mL64.0123 mL128.0246 mL
5mM1.2802 mL6.4012 mL12.8025 mL25.6049 mL
10mM0.6401 mL3.2006 mL6.4012 mL12.8025 mL
20mM0.3201 mL1.6003 mL3.2006 mL6.4012 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.