2MeSADP

This product is for research use only, not for human use. We do not sell to patients.

2MeSADP
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$1500To Be Confirmed
100mg$2300To Be Confirmed
200mg$3450To Be Confirmed

Cat #: V3528 CAS #: 475193-31-8 Purity ≥ 98%

Description: 2MeSADP is a novel and potent purinergic agonist which acts by displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors and inhibiting cAMP accumulation.

References: Zhang FL, et al. P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse. J Pharmacol Exp Ther. 2002;301(2):705-713.

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Product Promise

Promise
Molecular Weight (MW)539.24
Molecular FormulaC11H14N5Na3O10P2S
CAS No.475193-31-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn Vitro2-Methylthioadenosine diphosphate trisodium (2-Methylthio-ADP trisodium) is a powerful aggregating agent for human platelets. 2-Methylthioadenosine diphosphate trisodium is also a powerful inhibitor of the accumulation of cyclic AMP in intact platelets exposed to PGE1 and a phosphodiesterase inhibitor
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8545 mL9.2723 mL18.5446 mL37.0892 mL
5mM0.3709 mL1.8545 mL3.7089 mL7.4178 mL
10mM0.1854 mL0.9272 mL1.8545 mL3.7089 mL
20mM0.0927 mL0.4636 mL0.9272 mL1.8545 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.