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26S proteasome inhibitor I

This product is for research use only, not for human use. We do not sell to patients.

26S proteasome inhibitor I
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1250To Be Confirmed
250mg$1950To Be Confirmed
500mg$2925To Be Confirmed
email: [email protected]        [email protected]

Cat #: V2424 CAS #: 858557-69-4 Purity ≥ 99%

Description: 26S proteasome inhibitor I is a novel and potent inhibitor of 26S proteasome with potential anticancer activity.

References: Parlati F, et, al. Novel substrate for rpn 11 enzymatic activity. WO2006128196A2.

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Molecular Weight (MW)407.46
Molecular FormulaC23H25N3O4
CAS No.858557-69-4
Synonyms20S Proteasome-IN-1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4542 mL12.2711 mL24.5423 mL49.0846 mL
5mM0.4908 mL2.4542 mL4.9085 mL9.8169 mL
10mM0.2454 mL1.2271 mL2.4542 mL4.9085 mL
20mM0.1227 mL0.6136 mL1.2271 mL2.4542 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.