2-Furoic acid

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50g	$250	Check With Us
100g	$300	Check With Us
200g	$450	Check With Us

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Cat #: V9382 CAS #: 88-14-2 Purity ≥ 99%

Description: 2-Furoic acid is an orally bioactive heterocyclic carboxylic acid acting as a human cathepsin K inhibitor and is effective in lowering both serum cholesterol and serum triglyceride levels significantly in rats with an elevation of HDL cholesterol level at 20 mg/kg/day orally.

References: Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	112.08
Molecular Formula	C5H4O3
CAS No.	88-14-2
SMILES Code	O=C(C1=CC=CO1)O
Synonyms	2-Furoic acid; 2 Furoic acid; Kyselina 2-furoova; 2Furoic acid; alpha-Furancarboxylic acid; alpha-Furoic acid;

Protocol	In Vivo	2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	8.9222 mL	44.6110 mL	89.2220 mL	178.4440 mL
5mM	1.7844 mL	8.9222 mL	17.8444 mL	35.6888 mL
10mM	0.8922 mL	4.4611 mL	8.9222 mL	17.8444 mL
20mM	0.4461 mL	2.2305 mL	4.4611 mL	8.9222 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.