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10-Deacetylbaccatin-III (10-DAB)

This product is for research use only, not for human use. We do not sell to patients.

10-Deacetylbaccatin-III (10-DAB)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$275Check With Us
1g$470Check With Us
5g$1190Check With Us

Cat #: V2324 CAS #: 32981-86-5 Purity ≥ 98%

Description: 10-Deacetylbaccatin-III (also known as 10-DAB, 10-Deacetylbaccatin) is an intermediate with anticancer activities.

References: Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26.

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Molecular Weight (MW)544.59
Molecular FormulaC29H36O10
CAS No.32981-86-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 109 mg/mL (200.2 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=C(O[C@@H]([C@@]1([H])[C@@]2(C)[C@@H](O)C[C@@]3([H])OC[C@]31OC(C)=O)[C@]4(O)C[C@H](O)C(C)=C(C4(C)C)[C@@H](O)C2=O)C5=CC=CC=C5
Synonyms10DAB; 10DAB III
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8362 mL9.1812 mL18.3624 mL36.7249 mL
5mM0.3672 mL1.8362 mL3.6725 mL7.3450 mL
10mM0.1836 mL0.9181 mL1.8362 mL3.6725 mL
20mM0.0918 mL0.4591 mL0.9181 mL1.8362 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.